Cheng WA, Chan YW 2004

ABSTRACT

SNPs are single base pair mutations which occur with a high frequency (>=1% in population) throughout the genome. Many SNPs have been found to be highly linked to some human diseases. Optimal primer sequence is essential for SNP genotyping which is a process for identifying and measuring the presence of SNPs. The primers for genotyping need to bind the target region flanking the SNP specifically and efficiently. Bioinformatics has evolved to comprise of a set of essential tools for biological research and has enhanced research processes enormously due to the high speed computation and vast memory capacity of computers. This software kit (SEP) is a bioinformatics application used to aid in designing the suitable primers for SNP experiments.